Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses.

Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses.

<h4>Background</h4>Brain iron deposition has been linked to several neurodegenerative conditions and reported in alcohol dependence. Whether iron accumulation occurs in moderate drinkers is unknown. Our objectives were to investigate evidence in support of causal relationships between al...

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Main Authors: Anya Topiwala, Chaoyue Wang, Klaus P Ebmeier, Stephen Burgess, Steven Bell, Daniel F Levey, Hang Zhou, Celeste McCracken, Adriana Roca-Fernández, Steffen E Petersen, Betty Raman, Masud Husain, Joel Gelernter, Karla L Miller, Stephen M Smith, Thomas E Nichols
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1004039&type=printable
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https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1004039&type=printable

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