2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol): blood content in rats after intravenous administration and chemical resistance

Background. The domestic antitumor compound 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) has high antitumor activity on a wide range of experimental tumors.Goal. To study the content of chlonisol in the blood of rats at different times after intravenous administration and its ch...

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Main Authors: V. A. Alexandrov, G. V. Tochilnikov, S. V. Shatik, A. N. Stukov, O. A. Beljaeva, E. V. Bashkatova, V. G. Dranishnikov, T. Yu. Semiglazova
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2025-01-01
Series:Фармакокинетика и Фармакодинамика
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Online Access:https://www.pharmacokinetica.ru/jour/article/view/435
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