Single-atom Zr doped heterojunction enhanced piezocatalysis for implant infection therapy through synergistic metal immunotherapy with sonodynamic and physical puncture

Single-atom Zr doped heterojunction enhanced piezocatalysis for implant infection therapy through synergistic metal immunotherapy with sonodynamic and physical puncture

Abstract Recent common clinical treatments for implant bacterial infections involve replacing inert implants and using antibiotics. However, these methods remain limited in their effectiveness for pathogen clearance, immune regulation, and osteogenesis. In this study, we developed a Zr-doped heteroi...

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Main Authors: Xing Zhou, Jingbo Xie, Xingchen Zhou, Tianyou Ma, Yichen Lu, Yiwen Yang, Zhefei Xie, Houfu Ling, Rui Xu, Mo Wu, Jinglei Wang, Weixiang Wang, Derong Kong, Pengchao Xu, Xuan Wan, Hongbo Wu, Peijian Tong, Hanting Xia
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Nanobiotechnology
Subjects:
Piezocatalysis
Sonodynamic therapy
Metalloimmunotherapy
Antibacterial
Bone formation
Online Access:https://doi.org/10.1186/s12951-025-03309-x
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https://doi.org/10.1186/s12951-025-03309-x

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