The identification of XPR1 as a voltage- and phosphate-activated phosphate-permeable ion channel

Abstract Maintaining a balance of inorganic phosphate (Pi) is vital for cellular functionality. Proper phosphate levels are managed through Pi import and export; and the processes governing Pi export remain the least understood. Xenotropic and Polytropic retrovirus Receptor 1 (XPR1) has been identif...

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Bibliographic Details
Main Authors: Hongjiang Wu, Liang Sun, Tong Huo, Theodore G. Wensel, Frank T. Horrigan, Zhao Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59678-2
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