Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video)
AimsThis study aimed to compare the clinical outcomes of patients with submucosal tumors treated with endoscopic submucosal excavation (ESE) and those treated with mucosal snare resection-endoscopic submucosal excavation (MSR-ESE).MethodsWe retrospectively analyzed clinical data from patients who un...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1534196/full |
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| author | Wei Wei Xiaolong Zheng Yongli Ye Hongxia Li Yiping Hong Jianting Cai |
| author_facet | Wei Wei Xiaolong Zheng Yongli Ye Hongxia Li Yiping Hong Jianting Cai |
| author_sort | Wei Wei |
| collection | DOAJ |
| description | AimsThis study aimed to compare the clinical outcomes of patients with submucosal tumors treated with endoscopic submucosal excavation (ESE) and those treated with mucosal snare resection-endoscopic submucosal excavation (MSR-ESE).MethodsWe retrospectively analyzed clinical data from patients who underwent ESE or MSR-ESE at the Second Affiliated Hospital of Zhejiang University School of Medicine between January 2023 and January 2024. Factors such as operation time, intraoperative perforation, postoperative adverse events, postoperative fasting time, antibiotic use, hospitalization duration, costs, and pathological diagnosis were compared between the two procedures.ResultsA total of 180 patients with submucosal tumors were included in this study. The MSR-ESE group consisted of 75 patients (41.7%), while the ESE group had 105 patients (58.3%). Propensity score matching (PSM) showed no significant differences in postoperative antibiotic use, fasting time, or intraoperative perforation between the two groups (P>0.05). However, the MSR-ESE group demonstrated shorter operation and hospitalization times, lower hospitalization costs, and a reduced incidence of postoperative peritonitis (P<0.05). Multivariate logistic regression analysis identified operation time as an independent risk factor for unplanned intraoperative perforation, with the likelihood of perforation increasing significantly as operation time increased (P=0.007, OR=1.015, 95% CI, 1.004 to 1.026).ConclusionMSR-ESE outperforms ESE with shorter operation times, lower costs, and fewer postoperative complications, making it a safe and effective treatment for gastric submucosal tumors. |
| format | Article |
| id | doaj-art-4044ad6aaa7c4f6e96cb462f16a69069 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-4044ad6aaa7c4f6e96cb462f16a690692025-01-24T05:21:23ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011510.3389/fonc.2025.15341961534196Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video)Wei Wei0Xiaolong Zheng1Yongli Ye2Hongxia Li3Yiping Hong4Jianting Cai5Department of Gastroenterology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Gastroenterology, The Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, ChinaDepartment of Gastroenterology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaAimsThis study aimed to compare the clinical outcomes of patients with submucosal tumors treated with endoscopic submucosal excavation (ESE) and those treated with mucosal snare resection-endoscopic submucosal excavation (MSR-ESE).MethodsWe retrospectively analyzed clinical data from patients who underwent ESE or MSR-ESE at the Second Affiliated Hospital of Zhejiang University School of Medicine between January 2023 and January 2024. Factors such as operation time, intraoperative perforation, postoperative adverse events, postoperative fasting time, antibiotic use, hospitalization duration, costs, and pathological diagnosis were compared between the two procedures.ResultsA total of 180 patients with submucosal tumors were included in this study. The MSR-ESE group consisted of 75 patients (41.7%), while the ESE group had 105 patients (58.3%). Propensity score matching (PSM) showed no significant differences in postoperative antibiotic use, fasting time, or intraoperative perforation between the two groups (P>0.05). However, the MSR-ESE group demonstrated shorter operation and hospitalization times, lower hospitalization costs, and a reduced incidence of postoperative peritonitis (P<0.05). Multivariate logistic regression analysis identified operation time as an independent risk factor for unplanned intraoperative perforation, with the likelihood of perforation increasing significantly as operation time increased (P=0.007, OR=1.015, 95% CI, 1.004 to 1.026).ConclusionMSR-ESE outperforms ESE with shorter operation times, lower costs, and fewer postoperative complications, making it a safe and effective treatment for gastric submucosal tumors.https://www.frontiersin.org/articles/10.3389/fonc.2025.1534196/fullsubmucosal neoplasmsESEMSR-ESEendoscopic surgeryefficacy and safety |
| spellingShingle | Wei Wei Xiaolong Zheng Yongli Ye Hongxia Li Yiping Hong Jianting Cai Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video) Frontiers in Oncology submucosal neoplasms ESE MSR-ESE endoscopic surgery efficacy and safety |
| title | Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video) |
| title_full | Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video) |
| title_fullStr | Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video) |
| title_full_unstemmed | Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video) |
| title_short | Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video) |
| title_sort | mucosal snare resection endoscopic submucosal excavation for gastric submucosal tumors a retrospective study with video |
| topic | submucosal neoplasms ESE MSR-ESE endoscopic surgery efficacy and safety |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1534196/full |
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