Oligodendroglial heterogeneity in health, disease, and recovery: deeper insights into myelin dynamics

Oligodendroglial heterogeneity in health, disease, and recovery: deeper insights into myelin dynamics

Decades of research asserted that the oligodendroglial lineage comprises two cell types: oligodendrocyte precursor cells and oligodendrocytes. However, recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states, prompting a revision of the existing terminology. G...

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Bibliographic Details
Main Authors: Pieter-Jan Serneels, Julie D. De Schutter, Lies De Groef, Lieve Moons, Steven Bergmans
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-11-01
Series:Neural Regeneration Research
Subjects:
animal models
demyelination
fish
mammals
multiple sclerosis
myelin
neurodegeneration
oligodendrocytes
oligodendroglial lineage
remyelination
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-00694
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https://journals.lww.com/10.4103/NRR.NRR-D-24-00694

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