In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea
The present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root) of these medicinal plants ob...
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| Format: | Article |
| Language: | English |
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Sciendo
2018-06-01
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| Series: | Acta Pharmaceutica |
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| Online Access: | https://doi.org/10.2478/acph-2018-0012 |
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| author | Rizvi Tania Shamim Khan Abdul Latif Ali Liaqat Al-Mawali Narjis Mabood Fazal Hussain Javid Adnan Muhammad Al-Harrasi Ahmed |
| author_facet | Rizvi Tania Shamim Khan Abdul Latif Ali Liaqat Al-Mawali Narjis Mabood Fazal Hussain Javid Adnan Muhammad Al-Harrasi Ahmed |
| author_sort | Rizvi Tania Shamim |
| collection | DOAJ |
| description | The present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root) of these medicinal plants obtained in n-hexane, chloroform, n-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC) of both selected medicinal plants was also evaluated. The results indicated that extracts of T. apollinea leaf, stem and root have higher TPC compared to those of C. colocynthis. Similarly, the results of the present study revealed higher bioactivity of C. colocynthis than that of T. apollinea in various antioxidant assays. Various plant parts of each plant were also compared. |
| format | Article |
| id | doaj-art-3fe7ca7b060a4f60a78444960680a5f3 |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2018-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-3fe7ca7b060a4f60a78444960680a5f32025-02-02T11:05:46ZengSciendoActa Pharmaceutica1846-95582018-06-0168223524210.2478/acph-2018-0012acph-2018-0012In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollineaRizvi Tania Shamim0Khan Abdul Latif1Ali Liaqat2Al-Mawali Narjis3Mabood Fazal4Hussain Javid5Adnan Muhammad6Al-Harrasi Ahmed7UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, OmanUoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, OmanUoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, OmanUoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, OmanDepartment of Biological Science and Chemistry, University of Nizwa, Birkat Al-Mouz, Nizwa-616, OmanDepartment of Biological Science and Chemistry, University of Nizwa, Birkat Al-Mouz, Nizwa-616, OmanDepartment of Botany, Kohat University of Science and Technology, Kohat-26000, PakistanUoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, OmanThe present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root) of these medicinal plants obtained in n-hexane, chloroform, n-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC) of both selected medicinal plants was also evaluated. The results indicated that extracts of T. apollinea leaf, stem and root have higher TPC compared to those of C. colocynthis. Similarly, the results of the present study revealed higher bioactivity of C. colocynthis than that of T. apollinea in various antioxidant assays. Various plant parts of each plant were also compared.https://doi.org/10.2478/acph-2018-0012citrullus colocynthistephrosia apollineaoxidative stresstotal phenolics |
| spellingShingle | Rizvi Tania Shamim Khan Abdul Latif Ali Liaqat Al-Mawali Narjis Mabood Fazal Hussain Javid Adnan Muhammad Al-Harrasi Ahmed In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea Acta Pharmaceutica citrullus colocynthis tephrosia apollinea oxidative stress total phenolics |
| title | In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea |
| title_full | In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea |
| title_fullStr | In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea |
| title_full_unstemmed | In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea |
| title_short | In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea |
| title_sort | in vitro oxidative stress regulatory potential of citrullus colocynthis and tephrosia apollinea |
| topic | citrullus colocynthis tephrosia apollinea oxidative stress total phenolics |
| url | https://doi.org/10.2478/acph-2018-0012 |
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