RNF138 contributes to cisplatin resistance in nasopharyngeal carcinoma cells

RNF138 contributes to cisplatin resistance in nasopharyngeal carcinoma cells

Abstract Resistance to chemotherapy is a significant concern in the treatment of nasopharyngeal carcinoma (NPC), and occurs due to various mechanisms. This study is aimed to evaluate the effects of RING finger protein 138 (RNF138) in the development of cisplatin resistance to NPC. After gene overexp...

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Bibliographic Details
Main Authors: Hangyu Xu, Qing Yin, Linna Fan, Yating Zhao, Biying Song, Qifan Xu, Jie Zhu, Meifen Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Nasopharyngeal carcinoma
RNF138
Cisplatin resistance
Proliferation
Apoptosis
DNA damage
Online Access:https://doi.org/10.1038/s41598-025-85716-6
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https://doi.org/10.1038/s41598-025-85716-6

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