Genomic Differences and Distinct TP53 Mutation Site‐Linked Chemosensitivity in Early‐ and Late‐Onset Gastric Cancer

Genomic Differences and Distinct TP53 Mutation Site‐Linked Chemosensitivity in Early‐ and Late‐Onset Gastric Cancer

ABSTRACT Background Gastric cancer (GC) in younger patients often exhibits aggressive behavior and a poorer prognosis than that in older patients. Although the clinical differences may stem from oncogenic gene variations, it is unclear whether genetic differences exist between these groups. This stu...

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Main Authors: Tomohiro Kamio, Yoshiyasu Kono, Kensuke Hirosuna, Toshiki Ozato, Hideki Yamamoto, Akira Hirasawa, Daisuke Ennishi, Shuta Tomida, Shinichi Toyooka, Motoyuki Otsuka
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Cancer Medicine
Subjects:
comprehensive genomic profiling
early‐onset gastric cancer
oxaliplatin
TP53
Online Access:https://doi.org/10.1002/cam4.70793
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https://doi.org/10.1002/cam4.70793

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