Immediate or delayed initiation of renal replacement therapy in patients with leptospirosis and acute kidney injury: a target trial emulation

Abstract Background Anecdotal evidence suggests that early renal replacement therapy (RRT) may improve the mortality associated with acute kidney injury (AKI) in patients with leptospirosis. Conversely, several randomized controlled trials (RCTs) conducted in intensive care units have refuted the po...

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Bibliographic Details
Main Authors: Marie Julien, Cédric Rafat, Loïc Raffray, Henri Vacher-Coponat, Nicolas Allou, Jérôme Allyn, Julien Jabot, Yannis Lombardi
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Annals of Intensive Care
Online Access:https://doi.org/10.1186/s13613-025-01477-5
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