Noncanonical PRC1.1 targets BTG2 to retain cyclin gene expression and cell growth in neuroblastoma

Abstract Cancer cells exploit epigenetic modifications and post-transcriptional regulations to form oncogenic gene expression networks. However, how these machineries collaboratively orchestrate malignancy remains elusive. One of aberrant epigenetic pathways in cancer is Polycomb repressive complex...

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Bibliographic Details
Main Authors: Shunpei Satoh, Mariko Hasegawa, Ryu Okada, Masayuki Haruta, Hisanori Takenobu, Miki Ohira, Takehiko Kamijo
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-025-00561-6
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