Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias

Pulsed field ablation (PFA) is a catheter-based procedure that utilizes short high voltage and short-duration electrical field pulses to induce tissue injury. The last decade has yielded significant scientific progress and quickened interest in PFA as an energy modality leading to the emergence of t...

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Main Authors: Hagai Yavin, Mark Prasad, Jonathan Gordon, Tolga Aksu, Henry D. Huang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/12/1/10
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author Hagai Yavin
Mark Prasad
Jonathan Gordon
Tolga Aksu
Henry D. Huang
author_facet Hagai Yavin
Mark Prasad
Jonathan Gordon
Tolga Aksu
Henry D. Huang
author_sort Hagai Yavin
collection DOAJ
description Pulsed field ablation (PFA) is a catheter-based procedure that utilizes short high voltage and short-duration electrical field pulses to induce tissue injury. The last decade has yielded significant scientific progress and quickened interest in PFA as an energy modality leading to the emergence of the clinical use of PFA technologies for the treatment of atrial fibrillation. It is generally agreed that more research is needed to improve our biophysical understanding of PFA for clinical cardiac applications as well as its potential as a potential alternative energy source to thermal ablation modalities for the treatment of other arrhythmias. In this review, we discuss the available preclinical and clinical evidence for PFA for atrial fibrillation, developments for ventricular arrhythmia (VA) ablation, and future perspectives.
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institution Kabale University
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series Journal of Cardiovascular Development and Disease
spelling doaj-art-3edf84e3aad040bfb9d9ccec5d70f7802025-01-24T13:35:58ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252024-12-011211010.3390/jcdd12010010Contemporary Trends in Pulsed Field Ablation for Cardiac ArrhythmiasHagai Yavin0Mark Prasad1Jonathan Gordon2Tolga Aksu3Henry D. Huang4Department of Cardiology, Rush University Medical Center, Chicago, IL 60612, USADepartment of Cardiology, Rush University Medical Center, Chicago, IL 60612, USADepartment of Cardiology, Rush University Medical Center, Chicago, IL 60612, USADepartment of Cardiology, Yeditepe University Hospital, 34755 Istanbul, TurkeyDepartment of Cardiology, Rush University Medical Center, Chicago, IL 60612, USAPulsed field ablation (PFA) is a catheter-based procedure that utilizes short high voltage and short-duration electrical field pulses to induce tissue injury. The last decade has yielded significant scientific progress and quickened interest in PFA as an energy modality leading to the emergence of the clinical use of PFA technologies for the treatment of atrial fibrillation. It is generally agreed that more research is needed to improve our biophysical understanding of PFA for clinical cardiac applications as well as its potential as a potential alternative energy source to thermal ablation modalities for the treatment of other arrhythmias. In this review, we discuss the available preclinical and clinical evidence for PFA for atrial fibrillation, developments for ventricular arrhythmia (VA) ablation, and future perspectives.https://www.mdpi.com/2308-3425/12/1/10pulsed field ablationcryoablationradiofrequencyatrial fibrillationventricular tachycardia
spellingShingle Hagai Yavin
Mark Prasad
Jonathan Gordon
Tolga Aksu
Henry D. Huang
Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias
Journal of Cardiovascular Development and Disease
pulsed field ablation
cryoablation
radiofrequency
atrial fibrillation
ventricular tachycardia
title Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias
title_full Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias
title_fullStr Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias
title_full_unstemmed Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias
title_short Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias
title_sort contemporary trends in pulsed field ablation for cardiac arrhythmias
topic pulsed field ablation
cryoablation
radiofrequency
atrial fibrillation
ventricular tachycardia
url https://www.mdpi.com/2308-3425/12/1/10
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