A dual-phase biologic augmentation of rotator cuff healing in a preclinical rat model using interleukin-17F and low-dose lithium

A dual-phase biologic augmentation of rotator cuff healing in a preclinical rat model using interleukin-17F and low-dose lithium

Background: Rotator cuff tendon tears are a common cause of shoulder dysfunction in adults. Yet, impaired healing continues to result in higher failure rates after surgical repair resulting in patient dysfunction and prolonged recovery. This has spurred increased investigation of biologic augmentati...

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Main Authors: Manisha R. Mistry, MD, MSc, Yufa Wang, MD, MSc, Cari M. Whyne, PhD, David M. Phillips, MSc, Wendy Oakden, PhD, Paul Marks, MD, Jimmy Tat, MD, MSc, Diane Nam, MD, MSc
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:JSES International
Subjects:
Rotator cuff healing
Cytokines
IL-17F
Lithium carbonate
Rat model
Rotator cuff repair
Online Access:http://www.sciencedirect.com/science/article/pii/S2666638324004742
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