Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma
Numb chin syndrome is a rare sensory neuropathy of the mental nerve characterized by numbness, hypoesthesia, paraesthesia, and very rarely pain. Dental causes, especially iatrogenic ones, maxillofacial trauma, or malignant neoplasm are etiologic factors for this rare syndrome. Many malignant and met...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2014/413162 |
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| author | Mario Carbone Francesco Della Ferrera Lucio Carbone Gaia Gatti Marco Carrozzo |
| author_facet | Mario Carbone Francesco Della Ferrera Lucio Carbone Gaia Gatti Marco Carrozzo |
| author_sort | Mario Carbone |
| collection | DOAJ |
| description | Numb chin syndrome is a rare sensory neuropathy of the mental nerve characterized by numbness, hypoesthesia, paraesthesia, and very rarely pain. Dental causes, especially iatrogenic ones, maxillofacial trauma, or malignant neoplasm are etiologic factors for this rare syndrome. Many malignant and metastatic neoplasms are causing this syndrome, like primary osteosarcoma, squamous cell carcinoma, and mandibular metastasis of primary carcinoma of breast, lung, thyroid, kidney, prostate, and nasopharynx. Haematological malignancies like acute lymphocytic leukaemia, Hodgkin and non-Hodgkin lymphoma, and myeloma can cause this neuropathy. The authors report a case of a 71-year-old woman in which the numb chin syndrome was the first symptom of the diffuse large B-cell lymphoma, which caused infiltration and reabsorption of the alveolar ridge and lower mandibular cortex. A biopsy of the mass was performed on fragments of tissue collected from the mandibular periosteum, medullary and cortical mandibular bone, and inferior alveolar nerve. |
| format | Article |
| id | doaj-art-3ec35169ab8f48f38535b71c9d3db7b8 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-3ec35169ab8f48f38535b71c9d3db7b82025-02-03T01:00:17ZengWileyCase Reports in Dentistry2090-64472090-64552014-01-01201410.1155/2014/413162413162Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell LymphomaMario Carbone0Francesco Della Ferrera1Lucio Carbone2Gaia Gatti3Marco Carrozzo4Department of Surgical Sciences, Oral Medicine Section, CIR Dental School, University of Turin, Via Nizza 230, 10126 Turin, ItalyDepartment of Surgical Sciences, Oral Medicine Section, CIR Dental School, University of Turin, Via Nizza 230, 10126 Turin, ItalyPrivate Practice, Turin, ItalyDepartment of Medical Sciences, Section of Pathology, San Giovanni Battista Hospital, Strada Comunale di S. Vito Revigliasco 34, 10133 Torino, ItalyOral Medicine Department, Centre for Oral Health Research, Newcastle University, Newcastle upon Tyne, Tyne and Wear NE1 7RU, UKNumb chin syndrome is a rare sensory neuropathy of the mental nerve characterized by numbness, hypoesthesia, paraesthesia, and very rarely pain. Dental causes, especially iatrogenic ones, maxillofacial trauma, or malignant neoplasm are etiologic factors for this rare syndrome. Many malignant and metastatic neoplasms are causing this syndrome, like primary osteosarcoma, squamous cell carcinoma, and mandibular metastasis of primary carcinoma of breast, lung, thyroid, kidney, prostate, and nasopharynx. Haematological malignancies like acute lymphocytic leukaemia, Hodgkin and non-Hodgkin lymphoma, and myeloma can cause this neuropathy. The authors report a case of a 71-year-old woman in which the numb chin syndrome was the first symptom of the diffuse large B-cell lymphoma, which caused infiltration and reabsorption of the alveolar ridge and lower mandibular cortex. A biopsy of the mass was performed on fragments of tissue collected from the mandibular periosteum, medullary and cortical mandibular bone, and inferior alveolar nerve.http://dx.doi.org/10.1155/2014/413162 |
| spellingShingle | Mario Carbone Francesco Della Ferrera Lucio Carbone Gaia Gatti Marco Carrozzo Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma Case Reports in Dentistry |
| title | Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma |
| title_full | Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma |
| title_fullStr | Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma |
| title_full_unstemmed | Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma |
| title_short | Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma |
| title_sort | numb chin syndrome as first symptom of diffuse large b cell lymphoma |
| url | http://dx.doi.org/10.1155/2014/413162 |
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