Enhancing selective itaconic acid synthesis in Yarrowia lipolytica through targeted metabolite transport reprogramming

Enhancing selective itaconic acid synthesis in Yarrowia lipolytica through targeted metabolite transport reprogramming

Abstract Background Itaconic acid is a valuable platform chemical with applications in polymer synthesis and other industrial sectors. Microbial fermentation offers a sustainable production route, involving two fungi such as Aspergillus terreus and Ustilago maydis. However, their employment in indus...

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Main Authors: Cosetta Ciliberti, Zbigniew Lazar, Kacper Szymański, Evgeniya Yuzbasheva, Tigran Yuzbashev, Ivan Laptev, Luigi Palmieri, Isabella Pisano, Gennaro Agrimi
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Yarrowia lipolytica
Itaconic acid
Transporters
Pathway diversification
Online Access:https://doi.org/10.1186/s13068-025-02668-9
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https://doi.org/10.1186/s13068-025-02668-9

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