Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer

Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer

Background: Bone metastasis remains one of the biggest challenges in the treatment of prostate cancer, and other solid tumors such as breast, lung, and colon. Modeling a complex microenvironment in-vitro such as the bone niche, requires interrogation of cell-cell interactions, specific extracellular...

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Bibliographic Details
Main Authors: Rebeca San Martin, Prijoyit Das, Tianchun Xue, Morgan Rose Brown, Renata Dos Reis Marques, Michael Essington, Adrian Gonzalez, Rachel Patton McCord
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Heliyon
Subjects:
Prostate cancer
Bone metastasis
Amorphous calcium phosphate
Cell culture modeling
Androgen resistance
Gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025003093
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