PALS1-dependent modulations of mRNA profiles in MDCK II cells grown in non-confluent monolayers and three-dimensional cysts

PALS1-dependent modulations of mRNA profiles in MDCK II cells grown in non-confluent monolayers and three-dimensional cysts

Abstract In epithelia, apicobasal cell polarization is closely linked to cell-cell contact formation, both controlled by the conserved Crumbs (CRB) complex, which includes the transmembrane protein Crumbs (CRB3a) and adapter proteins PALS1, PATJ, and LIN7c. In MDCK II cells, a model for cell polariz...

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Bibliographic Details
Main Authors: Klaus Schughart, Annika Möller-Kerutt, Verena Höffken, Pavel Nedvetsky, Ann-Christin Groh, Daniela Anne Braun, Hermann Pavenstädt, Thomas Weide
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Genomic Data
Subjects:
PALS1
Crumbs complex
Cell polarity
Junctions
Cell contacts
RNA sequencing
Online Access:https://doi.org/10.1186/s12863-024-01284-0
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https://doi.org/10.1186/s12863-024-01284-0

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