Depletion-restitution therapy for autoimmune rheumatic diseases. Part 1. Fundamental prerequisites and efficacy of modern treatment technologies: anti-B-cell drugs and CAR-T therapy

The key element in the pathogenesis of systemic autoimmune rheumatic diseases is the breakdown of immunological tolerance and the formation of a pool of autoreactive cells. This leads to uncontrolled activation of the effector arm of cellular (T-lymphocytes) and humoral (B-lymphocytes and plasma cel...

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Bibliographic Details
Main Authors: A. M. Lila, A. L. Maslyanskiy, D. A. Dibrov, A. V. Torgashina, E. G. Zotkin, M. Yu. Samsonov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2025-04-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/1734
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