Dasatinib and Quercetin Combination Increased Kidney Damage in Acute Folic Acid-Induced Experimental Nephropathy

Dasatinib and Quercetin Combination Increased Kidney Damage in Acute Folic Acid-Induced Experimental Nephropathy

<b>Background/Objectives</b>: Acute kidney injury (AKI) remains an unsolved medical problem due to the lack of effective treatments, high mortality, and increased susceptibility to progression to chronic kidney disease (CKD), especially in the elderly. Cellular senescence has been descri...

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Main Authors: Antonio Battaglia-Vieni, Vanessa Marchant, Lucia Tejedor-Santamaria, Cristina García-Caballero, Elena Flores-Salguero, María Piedad Ruiz-Torres, Sandra Rayego-Mateos, Ana Belen Sanz, Alberto Ortiz, Marta Ruiz-Ortega
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceuticals
Subjects:
acute kidney injury
senolytics
senescence
dasatinib
quercetin
Klotho
Online Access:https://www.mdpi.com/1424-8247/18/6/822
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