Dimethyl Fumarate Strongly Ameliorates Gray and White Matter Brain Injury and Modulates Glial Activation after Severe Hypoxia–Ischemia in Neonatal Rats

Dimethyl Fumarate Strongly Ameliorates Gray and White Matter Brain Injury and Modulates Glial Activation after Severe Hypoxia–Ischemia in Neonatal Rats

Neonatal hypoxia–ischemia is a major cause of infant death and disability. The only clinically accepted treatment is therapeutic hypothermia; however, cooling is less effective in the most severely encephalopathic infants. Here, we wanted to test the neuroprotective effect of the antioxidant dimethy...

Full description

Saved in:
Bibliographic Details
Main Authors: Jon Ander Alart, Antonia Álvarez, Ana Catalan, Borja Herrero de la Parte, Daniel Alonso-Alconada
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Antioxidants
Subjects:
neonatal brain injury
hypoxia–ischemia
dimethyl fumarate
neuroprotection
white matter injury
microglia
Online Access:https://www.mdpi.com/2076-3921/13/9/1122
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2076-3921/13/9/1122

Similar Items