Development of Solid Nanosystem for Delivery of Chlorhexidine with Increased Antimicrobial Activity and Decreased Cytotoxicity: Characterization and In Vitro and In Ovo Toxicological Screening

Development of Solid Nanosystem for Delivery of Chlorhexidine with Increased Antimicrobial Activity and Decreased Cytotoxicity: Characterization and In Vitro and In Ovo Toxicological Screening

The evaluation of chlorhexidine-carrier nanosystems based on iron oxide magnetic nanoparticles (IOMNPs), has gained significant attention in recent years due to the unique properties of the magnetic nanoparticles (NPSs). Chlorhexidine (CHX), a well-established antimicrobial agent, has been widely us...

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Main Authors: Alexandra-Ioana Dănilă, Mihai Romînu, Krisztina Munteanu, Elena-Alina Moacă, Andreea Geamantan-Sîrbu, Iustin Olariu, Diana Marian, Teodora Olariu, Ioana-Cristina Talpoş-Niculescu, Raluca Mioara Cosoroabă, Ramona Popovici, Ştefania Dinu
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
maghemite
chlorhexidine digluconate solution
human immortalized keratinocytes
murine epidermal cells
in vitro and in ovo screening
irritant potential
Online Access:https://www.mdpi.com/1420-3049/30/1/162
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