Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by loss of synapses and disrupted functional connectivity (FC) across different brain regions. Early in AD progression, tau pathology is found in the locus coeruleus (LC) prior to amyloid-induced exacerbation of clini...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2019/6981268 |
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