Vascular inflammation in chronic kidney disease: the role of uremic toxins in macrophage activation

Vascular inflammation in chronic kidney disease: the role of uremic toxins in macrophage activation

Chronic kidney disease (CKD) is a progressive condition characterized by the gradual loss of kidney function, leading to the accumulation of uremic toxins in the bloodstream. These toxins play a pivotal role in mediating vascular inflammation, a key contributor to the high cardiovascular morbidity a...

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Bibliographic Details
Main Authors: Prabhash Kumar Jha, Toshiaki Nakano, Lucas Yuji Umesaki Itto, Miguel Cantadori Barbeiro, Adrien Lupieri, Elena Aikawa, Masanori Aikawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
chronic kidney disease (CKD)
inflammation
vascular disease
uremic toxins
indoxyl sulfate
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1574489/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1574489/full

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