Pacemaker Placement in Patients with Stroke-Mediated Autonomic Dysregulation

Lateral medullary syndrome (LMS) is an ischemic disease of the medulla oblongata, which involves the territory of the posterior inferior cerebellar artery. Lateral medullary syndrome is often missed as the cause of autonomic dysregulation in patients with recent brain stem stroke. Due to the locatio...

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Main Authors: Ali A. Alsaad, Christopher O. Austin, Maisha T. Robinson, Michael B. Phillips
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2017/6301430
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author Ali A. Alsaad
Christopher O. Austin
Maisha T. Robinson
Michael B. Phillips
author_facet Ali A. Alsaad
Christopher O. Austin
Maisha T. Robinson
Michael B. Phillips
author_sort Ali A. Alsaad
collection DOAJ
description Lateral medullary syndrome (LMS) is an ischemic disease of the medulla oblongata, which involves the territory of the posterior inferior cerebellar artery. Lateral medullary syndrome is often missed as the cause of autonomic dysregulation in patients with recent brain stem stroke. Due to the location of the baroreceptor regulatory center in the lateral medulla oblongata, patients with LMS occasionally have autonomic dysregulation-associated clinical manifestations. We report a case of LMS-associated autonomic dysregulation. The case presented as sinus arrest and syncope, requiring permanent pacemaker placement. A dual-chamber pacemaker was placed, after failure of conservative measures to alleviate the patient’s symptoms. Our case shows the importance of recognizing LMS as a potential cause for life-threatening arrhythmias, heart block, and symptomatic bradycardia. Placement of permanent pacemaker may be necessary in some patients with LMS presenting with syncope, secondary to sinus arrest.
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series Case Reports in Medicine
spelling doaj-art-3d5dc3050c3d417ea0e776c4323ff64d2025-02-03T05:50:11ZengWileyCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/63014306301430Pacemaker Placement in Patients with Stroke-Mediated Autonomic DysregulationAli A. Alsaad0Christopher O. Austin1Maisha T. Robinson2Michael B. Phillips3Department of Internal Medicine, Mayo Clinic, Jacksonville, FL 32224, USADivision of Cardiovascular Diseases, Mayo Clinic, Jacksonville, FL 32224, USADepartment of Neurology, Mayo Clinic, Jacksonville, FL 32224, USADepartment of Internal Medicine, Mayo Clinic, Jacksonville, FL 32224, USALateral medullary syndrome (LMS) is an ischemic disease of the medulla oblongata, which involves the territory of the posterior inferior cerebellar artery. Lateral medullary syndrome is often missed as the cause of autonomic dysregulation in patients with recent brain stem stroke. Due to the location of the baroreceptor regulatory center in the lateral medulla oblongata, patients with LMS occasionally have autonomic dysregulation-associated clinical manifestations. We report a case of LMS-associated autonomic dysregulation. The case presented as sinus arrest and syncope, requiring permanent pacemaker placement. A dual-chamber pacemaker was placed, after failure of conservative measures to alleviate the patient’s symptoms. Our case shows the importance of recognizing LMS as a potential cause for life-threatening arrhythmias, heart block, and symptomatic bradycardia. Placement of permanent pacemaker may be necessary in some patients with LMS presenting with syncope, secondary to sinus arrest.http://dx.doi.org/10.1155/2017/6301430
spellingShingle Ali A. Alsaad
Christopher O. Austin
Maisha T. Robinson
Michael B. Phillips
Pacemaker Placement in Patients with Stroke-Mediated Autonomic Dysregulation
Case Reports in Medicine
title Pacemaker Placement in Patients with Stroke-Mediated Autonomic Dysregulation
title_full Pacemaker Placement in Patients with Stroke-Mediated Autonomic Dysregulation
title_fullStr Pacemaker Placement in Patients with Stroke-Mediated Autonomic Dysregulation
title_full_unstemmed Pacemaker Placement in Patients with Stroke-Mediated Autonomic Dysregulation
title_short Pacemaker Placement in Patients with Stroke-Mediated Autonomic Dysregulation
title_sort pacemaker placement in patients with stroke mediated autonomic dysregulation
url http://dx.doi.org/10.1155/2017/6301430
work_keys_str_mv AT aliaalsaad pacemakerplacementinpatientswithstrokemediatedautonomicdysregulation
AT christopheroaustin pacemakerplacementinpatientswithstrokemediatedautonomicdysregulation
AT maishatrobinson pacemakerplacementinpatientswithstrokemediatedautonomicdysregulation
AT michaelbphillips pacemakerplacementinpatientswithstrokemediatedautonomicdysregulation