Inhibition of osteoclast differentiation by (1→3)-β-D-glucan from Alcaligenes faecalis (curdlan) and dectin-1 interaction via the syk proteolytic system
We previously demonstrated that curdlan, a dectin-1 agonist, inhibits osteoclast formation via proteolysis of spleen tyrosine kinase (syk). In this study, we elucidated the molecular mechanism underlying the inhibition of osteoclast differentiation via syk proteolysis upon interaction of curdlan and...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-03-01
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| Series: | Carbohydrate Polymer Technologies and Applications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666893925000234 |
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