A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs

A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs

Abstract Background Members of the Klebsiella pneumoniae species complex (KpSC) are opportunistic pathogens that cause severe and difficult-to-treat infections. KpSC are common in non-human niches, but the clinical relevance of these populations is disputed. Methods In this study, we analysed 3255 w...

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Main Authors: Marit A. K. Hetland, Mia A. Winkler, Håkon P. Kaspersen, Fredrik Håkonsholm, Ragna-Johanne Bakksjø, Eva Bernhoff, Jose F. Delgado-Blas, Sylvain Brisse, Annapaula Correia, Aasmund Fostervold, Margaret M. C. Lam, Bjørn-Tore Lunestad, Nachiket P. Marathe, Niclas Raffelsberger, Ørjan Samuelsen, Marianne Sunde, Arnfinn Sundsfjord, Anne Margrete Urdahl, Ryan R. Wick, Iren H. Löhr, Kathryn E. Holt
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Genome Medicine
Subjects:
One Health
Klebsiella pneumoniae species complex
Genomics
GWAS
AMR
Transmission
Online Access:https://doi.org/10.1186/s13073-025-01466-0
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https://doi.org/10.1186/s13073-025-01466-0

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