Identification of marker genes associated with oxidative stress in hypertrophic cardiomyopathy using bioinformatics analysis and experimental validation

Identification of marker genes associated with oxidative stress in hypertrophic cardiomyopathy using bioinformatics analysis and experimental validation

Abstract Hypertrophic cardiomyopathy (HCM) is a common inherited cardiomyopathy, and the mechanisms by which oxidative stress contributes to HCM remain unclear. This study aimed to identify HCM-associated oxidative stress genes and evaluate their significance in HCM pathogenesis through bioinformati...

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Bibliographic Details
Main Authors: Jian Zhuo, Ding Ding, Mengkang Fan, Weiwei Lu, Xiaochen Lu, Lihong Yao, Hongzhuan Sheng
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Bioinformatics
Heart
Hypertrophic cardiomyopathy
Diagnosis
Oxidative stress
Immune microenvironment
Online Access:https://doi.org/10.1038/s41598-025-14313-4
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https://doi.org/10.1038/s41598-025-14313-4

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