Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis

Heerfordt’s syndrome is a rare manifestation of sarcoidosis characterized by the presence of facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever. Two cases of Heerfordt’s syndrome and a literature review are presented. Case  1. A 53-year-old man presented with swelli...

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Main Authors: Keishi Fujiwara, Yasushi Furuta, Satoshi Fukuda
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2016/3642735
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author Keishi Fujiwara
Yasushi Furuta
Satoshi Fukuda
author_facet Keishi Fujiwara
Yasushi Furuta
Satoshi Fukuda
author_sort Keishi Fujiwara
collection DOAJ
description Heerfordt’s syndrome is a rare manifestation of sarcoidosis characterized by the presence of facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever. Two cases of Heerfordt’s syndrome and a literature review are presented. Case  1. A 53-year-old man presented with swelling of his right eyelid, right facial nerve palsy, and swelling of his right parotid gland. A biopsy specimen from the swollen eyelid indicated sarcoidosis and he was diagnosed with incomplete Heerfordt’s syndrome based on the absence of uveitis. His symptoms were improved by corticosteroid therapy. Case  2. A 55-year-old woman presented with left facial nerve palsy, bilateral hearing loss, and swelling of her bilateral parotid glands. She had been previously diagnosed with uveitis and bilateral hilar lymphadenopathy. Although no histological confirmation was performed, she was diagnosed with complete Heerfordt’s syndrome on the basis of her clinical symptoms. Swelling of the bilateral parotid glands and left facial nerve palsy were improved immediately by corticosteroid therapy. Sarcoidosis is a relatively uncommon disease for the otolaryngologist. However, the otolaryngologist may encounter Heerfordt’s syndrome as this syndrome presents with facial nerve palsy and swelling of the parotid gland. Therefore, we otolaryngologists should diagnose and treat Heerfordt’s syndrome appropriately in cooperation with pneumologists and ophthalmologists.
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spelling doaj-art-3cc2bf3963be4656b4c2a390ed4dfcad2025-02-03T01:26:44ZengWileyCase Reports in Otolaryngology2090-67652090-67732016-01-01201610.1155/2016/36427353642735Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of SarcoidosisKeishi Fujiwara0Yasushi Furuta1Satoshi Fukuda2Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Hokkaido University, N15W7, Kita-ku, Sapporo 0608638, JapanDepartment of Otolaryngology, Head and Neck Surgery, Teine-Keijinkai Hospital, 12-1-40 Maeda 1-Jo, Teine-Ku, Sapporo 0068555, JapanDepartment of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Hokkaido University, N15W7, Kita-ku, Sapporo 0608638, JapanHeerfordt’s syndrome is a rare manifestation of sarcoidosis characterized by the presence of facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever. Two cases of Heerfordt’s syndrome and a literature review are presented. Case  1. A 53-year-old man presented with swelling of his right eyelid, right facial nerve palsy, and swelling of his right parotid gland. A biopsy specimen from the swollen eyelid indicated sarcoidosis and he was diagnosed with incomplete Heerfordt’s syndrome based on the absence of uveitis. His symptoms were improved by corticosteroid therapy. Case  2. A 55-year-old woman presented with left facial nerve palsy, bilateral hearing loss, and swelling of her bilateral parotid glands. She had been previously diagnosed with uveitis and bilateral hilar lymphadenopathy. Although no histological confirmation was performed, she was diagnosed with complete Heerfordt’s syndrome on the basis of her clinical symptoms. Swelling of the bilateral parotid glands and left facial nerve palsy were improved immediately by corticosteroid therapy. Sarcoidosis is a relatively uncommon disease for the otolaryngologist. However, the otolaryngologist may encounter Heerfordt’s syndrome as this syndrome presents with facial nerve palsy and swelling of the parotid gland. Therefore, we otolaryngologists should diagnose and treat Heerfordt’s syndrome appropriately in cooperation with pneumologists and ophthalmologists.http://dx.doi.org/10.1155/2016/3642735
spellingShingle Keishi Fujiwara
Yasushi Furuta
Satoshi Fukuda
Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis
Case Reports in Otolaryngology
title Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis
title_full Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis
title_fullStr Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis
title_full_unstemmed Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis
title_short Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis
title_sort two cases of heerfordt s syndrome a rare manifestation of sarcoidosis
url http://dx.doi.org/10.1155/2016/3642735
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