Quantification of Circulating Cell-Free DNA as a NETosis Marker in Trauma Patients with Type 2 Diabetes Mellitus

Quantification of Circulating Cell-Free DNA as a NETosis Marker in Trauma Patients with Type 2 Diabetes Mellitus

Type 2 diabetes mellitus (T2DM) significantly impairs fracture healing, with neutrophils playing a crucial role in this process. In T2DM, these immune cells are over-activated, leading to the excessive release of neutrophil extracellular traps (NETs), increasing inflammation and hindering recovery....

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Bibliographic Details
Main Authors: Filiz Sahin, Regina Breinbauer, Caren Linnemann, Melike Tombaz, Andreas K. Nussler, Sabrina Ehnert
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Methods and Protocols
Subjects:
neutrophil extracellular traps
trauma
diabetes mellitus
NET marker
Online Access:https://www.mdpi.com/2409-9279/8/2/42
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