Camel milk is a neglected source of brucellosis among rural Arab communities
Abstract The World Health Organization describes brucellosis as one of the world’s leading zoonotic diseases, with the Middle East a global hotspot. Brucella melitensis is endemic among livestock populations in the region, with zoonotic transmission occurring via consumption of raw milk, amongst oth...
Saved in:
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-55737-2 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832585557834727424 |
|---|---|
| author | Peter Holloway Matthew Gibson Tanja Holloway Iain Pickett Brittany Crook Jacqueline M. Cardwell Stephen Nash Imadidden Musallam Bilal Al-Omari Ahmad Al-Majali Wail Hayajneh Ehab Abu-Basha Punam Mangtani Javier Guitian |
| author_facet | Peter Holloway Matthew Gibson Tanja Holloway Iain Pickett Brittany Crook Jacqueline M. Cardwell Stephen Nash Imadidden Musallam Bilal Al-Omari Ahmad Al-Majali Wail Hayajneh Ehab Abu-Basha Punam Mangtani Javier Guitian |
| author_sort | Peter Holloway |
| collection | DOAJ |
| description | Abstract The World Health Organization describes brucellosis as one of the world’s leading zoonotic diseases, with the Middle East a global hotspot. Brucella melitensis is endemic among livestock populations in the region, with zoonotic transmission occurring via consumption of raw milk, amongst other routes. Control is largely via vaccination of small ruminant and cattle populations. Due to sociocultural and religious influences camel milk (camelus dromedarius) is widely consumed raw, while milk from other livestock species is largely boiled. To investigate the potential public health impact of Brucella in camels we conduct a cross-sectional study in southern Jordan including 227 herds and 202 livestock-owning households. Here we show daily consumption of raw camel milk is associated with Brucella seropositive status among the study population, ORadj 2.19 (95%CI 1.23–3.94) on multivariable analysis, highlighting the need for socioculturally appropriate control measures; targeted interventions among the camel reservoir being crucial for effective control. |
| format | Article |
| id | doaj-art-3c96ea0f07ed48f5812c55f3567bb5c9 |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-3c96ea0f07ed48f5812c55f3567bb5c92025-01-26T12:42:09ZengNature PortfolioNature Communications2041-17232025-01-0116111410.1038/s41467-024-55737-2Camel milk is a neglected source of brucellosis among rural Arab communitiesPeter Holloway0Matthew Gibson1Tanja Holloway2Iain Pickett3Brittany Crook4Jacqueline M. Cardwell5Stephen Nash6Imadidden Musallam7Bilal Al-Omari8Ahmad Al-Majali9Wail Hayajneh10Ehab Abu-Basha11Punam Mangtani12Javier Guitian13Veterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre for Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, The Royal Veterinary CollegeVeterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre for Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, The Royal Veterinary CollegeDepartment of Infectious Disease Epidemiology and International Health, London School of Hygiene & Tropical MedicineVeterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre for Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, The Royal Veterinary CollegeVeterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre for Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, The Royal Veterinary CollegeVeterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre for Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, The Royal Veterinary CollegeDepartment of Medical Epidemiology and Biostatistics, Karolinska InstitutetVeterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre for Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, The Royal Veterinary CollegeFaculty of Veterinary Medicine, Jordan University of Science and TechnologyFaculty of Veterinary Medicine, Jordan University of Science and TechnologyDepartment of Paediatrics, School of Medicine, Saint Louis UniversityFaculty of Veterinary Medicine, Jordan University of Science and TechnologyDepartment of Infectious Disease Epidemiology and International Health, London School of Hygiene & Tropical MedicineVeterinary Epidemiology, Economics and Public Health Group, WOAH Collaborating Centre for Risk Analysis and Modelling, Department of Pathobiology and Population Sciences, The Royal Veterinary CollegeAbstract The World Health Organization describes brucellosis as one of the world’s leading zoonotic diseases, with the Middle East a global hotspot. Brucella melitensis is endemic among livestock populations in the region, with zoonotic transmission occurring via consumption of raw milk, amongst other routes. Control is largely via vaccination of small ruminant and cattle populations. Due to sociocultural and religious influences camel milk (camelus dromedarius) is widely consumed raw, while milk from other livestock species is largely boiled. To investigate the potential public health impact of Brucella in camels we conduct a cross-sectional study in southern Jordan including 227 herds and 202 livestock-owning households. Here we show daily consumption of raw camel milk is associated with Brucella seropositive status among the study population, ORadj 2.19 (95%CI 1.23–3.94) on multivariable analysis, highlighting the need for socioculturally appropriate control measures; targeted interventions among the camel reservoir being crucial for effective control.https://doi.org/10.1038/s41467-024-55737-2 |
| spellingShingle | Peter Holloway Matthew Gibson Tanja Holloway Iain Pickett Brittany Crook Jacqueline M. Cardwell Stephen Nash Imadidden Musallam Bilal Al-Omari Ahmad Al-Majali Wail Hayajneh Ehab Abu-Basha Punam Mangtani Javier Guitian Camel milk is a neglected source of brucellosis among rural Arab communities Nature Communications |
| title | Camel milk is a neglected source of brucellosis among rural Arab communities |
| title_full | Camel milk is a neglected source of brucellosis among rural Arab communities |
| title_fullStr | Camel milk is a neglected source of brucellosis among rural Arab communities |
| title_full_unstemmed | Camel milk is a neglected source of brucellosis among rural Arab communities |
| title_short | Camel milk is a neglected source of brucellosis among rural Arab communities |
| title_sort | camel milk is a neglected source of brucellosis among rural arab communities |
| url | https://doi.org/10.1038/s41467-024-55737-2 |
| work_keys_str_mv | AT peterholloway camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT matthewgibson camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT tanjaholloway camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT iainpickett camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT brittanycrook camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT jacquelinemcardwell camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT stephennash camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT imadiddenmusallam camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT bilalalomari camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT ahmadalmajali camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT wailhayajneh camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT ehababubasha camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT punammangtani camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities AT javierguitian camelmilkisaneglectedsourceofbrucellosisamongruralarabcommunities |