In SILICO Characterization of Technetium-99M Radiotracers: ADMET Properties and Protein Interaction Profiles

In SILICO Characterization of Technetium-99M Radiotracers: ADMET Properties and Protein Interaction Profiles

The rational design of technetium-99m (99mTc)-based radiopharmaceuticals requires a nuanced understanding of how physicochemical properties influence in vivo behavior and molecular interactions. In this study, we employed an integrated in silico framework to characterize ten clinically relevant 99mT...

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Bibliographic Details
Main Authors: V. Trusova, U. Malovytsia, P. Kuznietsov, I. Yakymenko, G. Gorbenko
Format: Article
Language:English
Published: V.N. Karazin Kharkiv National University Publishing 2025-06-01
Series:East European Journal of Physics
Subjects:
technetium-based radiotracers
human serum albumin
lysozyme
insulin
molecular docking
spect imaging
Online Access:https://periodicals.karazin.ua/eejp/article/view/26395
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