Lysine crotonylation in disease: mechanisms, biological functions and therapeutic targets
Abstract Lysine crotonylation (Kcr), a previously unknown post-translational modification (PTM), plays crucial roles in regulating cellular processes, including gene expression, chromatin remodeling, and cellular metabolism. Kcr is associated with various diseases, including neurodegenerative disord...
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| Main Authors: | Yu Ji, Shanshan Liu, Yiqiao Zhang, Yiyang Min, Luyang Wei, Chengjian Guan, Huajing Yu, Zhongtao Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
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| Series: | Epigenetics & Chromatin |
| Online Access: | https://doi.org/10.1186/s13072-025-00577-7 |
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