Arrest Peptide Profiling resolves co-translational folding pathways and chaperone interactions in vivo

Abstract Cytosolic proteins begin to fold co-translationally as soon as they emerge from the ribosome during translation. These early co-translational steps are crucial for overall folding and are guided by an intricate network of interactions with molecular chaperones. Because cellular co-translati...

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Bibliographic Details
Main Authors: Xiuqi Chen, Vincent J. Hilser, Christian M. Kaiser
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61398-6
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