Variation in Arterial CO2 is a Stronger Determinant of Brain Tissue Oxygenation Than its Synchronous Value in Critically Ill Patients With Acute Brain Injury

Variation in Arterial CO2 is a Stronger Determinant of Brain Tissue Oxygenation Than its Synchronous Value in Critically Ill Patients With Acute Brain Injury

OBJECTIVES:. In critically ill patients with acute brain injury (ABI), maintaining intracranial pressure (ICP) and brain tissue oxygenation (PbtO2) within targets could prevent secondary neurologic injury. Tight control of CO2 (Paco2), a potent regulator of cerebrovascular tone, is generally advocat...

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Main Authors: Joanie Martineau, MD, MSc, Francis Bernard, MD, Alexandrine Gagnon, MD, Virginie Williams, PhD, Sabrina Araujo de Franca, BSN, David Williamson, BPharm, PhD, Yiorgos Alexandros Cavayas, MD, Msc
Format: Article
Language:English
Published: Wolters Kluwer 2025-04-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000001241
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http://journals.lww.com/10.1097/CCE.0000000000001241

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