mosGILT antibodies interfere with Plasmodium sporogony in Anopheles gambiae

Abstract Plasmodium, the causative agents of malaria, are obtained by mosquitoes from an infected human. Following Plasmodium acquisition by Anopheles gambiae, mosquito gamma-interferon-inducible lysosomal thiol reductase (mosGILT) plays a critical role in its subsequent sporogony in the mosquito. A...

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Bibliographic Details
Main Authors: Brady Dolan, Tomás Correa Gaviria, Yuemei Dong, Peter Cresswell, George Dimopoulos, Yu-Min Chuang, Erol Fikrig
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-55902-1
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