Vascular cell‐specific roles of mineralocorticoid receptors in pulmonary hypertension

Vascular cell‐specific roles of mineralocorticoid receptors in pulmonary hypertension

Abnormalities that characterize pulmonary arterial hypertension include impairment in the structure and function of pulmonary vascular endothelial and smooth muscle cells. Aldosterone levels are elevated in human pulmonary arterial hypertension and in experimental pulmonary hypertension, while inhib...

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Main Authors: Divya P. Menon, Guanming Qi, Seung K. Kim, M. Elizabeth Moss, Krishna C. Penumatsa, Rod R. Warburton, Deniz Toksoz, Jamie Wilson, Nicholas S. Hill, Iris Z. Jaffe, Ioana R. Preston
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Pulmonary Circulation
Subjects:
pulmonary hypertension
experimental
right ventricle
spironolactone
mineralocorticoid receptor
endothelial cell
Online Access:https://doi.org/10.1177/20458940211025240
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https://doi.org/10.1177/20458940211025240

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