Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose Concentrations

We investigated possible variations of impedance values in samples of sodium chloride solution (sodium chloride 0.9%) with glucose at different concentrations, ranging from 5000 to around 75 mg/dL. The sodium chloride solution (either saline physiological solution) was chosen since it has similariti...

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Main Authors: Stefano Sbrignadello, Andrea Tura, Paolo Ravazzani
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Spectroscopy
Online Access:http://dx.doi.org/10.1155/2013/571372
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author Stefano Sbrignadello
Andrea Tura
Paolo Ravazzani
author_facet Stefano Sbrignadello
Andrea Tura
Paolo Ravazzani
author_sort Stefano Sbrignadello
collection DOAJ
description We investigated possible variations of impedance values in samples of sodium chloride solution (sodium chloride 0.9%) with glucose at different concentrations, ranging from 5000 to around 75 mg/dL. The sodium chloride solution (either saline physiological solution) was chosen since it has similarities to blood but no cell components, which may be confounding factors in this study. Special focus was on the effect of stirring and of temperature variations on the impedance spectrum of samples at different glucose concentrations. We found that variations in glucose concentration directly affect the impedance modulus of the sample both in static conditions and in dynamic conditions due to stirring, as well as at both room temperature and at increased temperature. In fact, even if the impedance variations were often small (around 3-4 mΩ per mg/dL), they were usually clearly measurable. These findings may be the basis for possible development of a new approach, based on impedance technology, for the noninvasive monitoring of glycaemia.
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institution Kabale University
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language English
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spelling doaj-art-3bce31d6c8e642998fa7e7d604e3f8282025-02-03T01:20:13ZengWileyJournal of Spectroscopy2314-49202314-49392013-01-01201310.1155/2013/571372571372Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose ConcentrationsStefano Sbrignadello0Andrea Tura1Paolo Ravazzani2Institute of Biomedical Engineering, National Research Council, Corso Stati Uniti 4, 35127 Padova, ItalyInstitute of Biomedical Engineering, National Research Council, Corso Stati Uniti 4, 35127 Padova, ItalyInstitute of Biomedical Engineering, National Research Council, Corso Stati Uniti 4, 35127 Padova, ItalyWe investigated possible variations of impedance values in samples of sodium chloride solution (sodium chloride 0.9%) with glucose at different concentrations, ranging from 5000 to around 75 mg/dL. The sodium chloride solution (either saline physiological solution) was chosen since it has similarities to blood but no cell components, which may be confounding factors in this study. Special focus was on the effect of stirring and of temperature variations on the impedance spectrum of samples at different glucose concentrations. We found that variations in glucose concentration directly affect the impedance modulus of the sample both in static conditions and in dynamic conditions due to stirring, as well as at both room temperature and at increased temperature. In fact, even if the impedance variations were often small (around 3-4 mΩ per mg/dL), they were usually clearly measurable. These findings may be the basis for possible development of a new approach, based on impedance technology, for the noninvasive monitoring of glycaemia.http://dx.doi.org/10.1155/2013/571372
spellingShingle Stefano Sbrignadello
Andrea Tura
Paolo Ravazzani
Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose Concentrations
Journal of Spectroscopy
title Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose Concentrations
title_full Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose Concentrations
title_fullStr Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose Concentrations
title_full_unstemmed Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose Concentrations
title_short Electroimpedance Spectroscopy for the Measurement of the Dielectric Properties of Sodium Chloride Solutions at Different Glucose Concentrations
title_sort electroimpedance spectroscopy for the measurement of the dielectric properties of sodium chloride solutions at different glucose concentrations
url http://dx.doi.org/10.1155/2013/571372
work_keys_str_mv AT stefanosbrignadello electroimpedancespectroscopyforthemeasurementofthedielectricpropertiesofsodiumchloridesolutionsatdifferentglucoseconcentrations
AT andreatura electroimpedancespectroscopyforthemeasurementofthedielectricpropertiesofsodiumchloridesolutionsatdifferentglucoseconcentrations
AT paoloravazzani electroimpedancespectroscopyforthemeasurementofthedielectricpropertiesofsodiumchloridesolutionsatdifferentglucoseconcentrations