Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous Media
Novel homoallylic alcohols incorporating sulfone moieties were synthesized by the treatment of different carbonyl compounds with allylic bromides in aqueous media via sonochemical Barbier-type reaction conditions. Sulfonation of α-bromoketones with sodium benzenesulfinate in presence of CuI/2,6-luti...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/364036 |
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| author | Mohamed F. Mady Ahmed A. El-Kateb Ibrahim F. Zeid Kåre B. Jørgensen |
| author_facet | Mohamed F. Mady Ahmed A. El-Kateb Ibrahim F. Zeid Kåre B. Jørgensen |
| author_sort | Mohamed F. Mady |
| collection | DOAJ |
| description | Novel homoallylic alcohols incorporating sulfone moieties were synthesized by the treatment of different carbonyl compounds with allylic bromides in aqueous media via sonochemical Barbier-type reaction conditions. Sulfonation of α-bromoketones with sodium benzenesulfinate in presence of CuI/2,6-lutidine rapidly gave β-keto-sulfones in good yields. In general, ultrasound irradiation offered the advantages of high yields, short reaction times, and simplicity compared to the conventional methods. The structures of all the compounds were confirmed by analytical and spectral data. |
| format | Article |
| id | doaj-art-3bb7746f861e49b89f025472c49aeb9c |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-3bb7746f861e49b89f025472c49aeb9c2025-02-03T01:10:51ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/364036364036Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous MediaMohamed F. Mady0Ahmed A. El-Kateb1Ibrahim F. Zeid2Kåre B. Jørgensen3Department of Mathematics and Natural Sciences, Faculty of Science and Technology, University of Stavanger, 4036 Stavanger, NorwayDepartment of Green Chemistry, National Research Centre, Dokki, Cairo 12622, EgyptChemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam, Menoufia 32515, EgyptDepartment of Mathematics and Natural Sciences, Faculty of Science and Technology, University of Stavanger, 4036 Stavanger, NorwayNovel homoallylic alcohols incorporating sulfone moieties were synthesized by the treatment of different carbonyl compounds with allylic bromides in aqueous media via sonochemical Barbier-type reaction conditions. Sulfonation of α-bromoketones with sodium benzenesulfinate in presence of CuI/2,6-lutidine rapidly gave β-keto-sulfones in good yields. In general, ultrasound irradiation offered the advantages of high yields, short reaction times, and simplicity compared to the conventional methods. The structures of all the compounds were confirmed by analytical and spectral data.http://dx.doi.org/10.1155/2013/364036 |
| spellingShingle | Mohamed F. Mady Ahmed A. El-Kateb Ibrahim F. Zeid Kåre B. Jørgensen Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous Media Journal of Chemistry |
| title | Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous Media |
| title_full | Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous Media |
| title_fullStr | Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous Media |
| title_full_unstemmed | Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous Media |
| title_short | Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous Media |
| title_sort | comparative studies on conventional and ultrasound assisted synthesis of novel homoallylic alcohol derivatives linked to sulfonyl dibenzene moiety in aqueous media |
| url | http://dx.doi.org/10.1155/2013/364036 |
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