Front instabilities and invasiveness of simulated 3D avascular tumors.

Front instabilities and invasiveness of simulated 3D avascular tumors.

We use the Glazier-Graner-Hogeweg model to simulate three-dimensional (3D), single-phenotype, avascular tumors growing in an homogeneous tissue matrix (TM) supplying a single limiting nutrient. We study the effects of two parameters on tumor morphology: a diffusion-limitation parameter defined as th...

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Bibliographic Details
Main Authors: Nikodem J Poplawski, Abbas Shirinifard, Ubirajara Agero, J Scott Gens, Maciej Swat, James A Glazier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0010641&type=printable
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