Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats
BACKGROUND: There is evidence that biguanides and sulfonylureas block diclofenac-induced antinociception (DIA) in rat models. However, little is known about the interaction between these hypoglycemics with respect to DIA.
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Main Author: | Mario I Ortiz |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | Pain Research and Management |
Online Access: | http://dx.doi.org/10.1155/2013/579183 |
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