Neurocognition as a major predictor of 8-week response to antipsychotics for drug-naïve first-episode schizophrenia using machine learning
Abstract Cognitive impairments are generally observed in patients with schizophrenia. However, it is unclear whether neurocognitive dysfunction can predict the efficacy of antipsychotics for first-episode schizophrenia (FES). Machine learning methods provide a relatively unbiased approach when evalu...
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| Main Authors: | Xianghe Wang, Tianqi Gao, Xiaodong Guo, Bingjie Huang, Yunfei Ji, Wanheng Hu, Xiaolin Yin, Yue Zheng, Chengcheng Pu, Xin Yu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Schizophrenia |
| Online Access: | https://doi.org/10.1038/s41537-025-00640-y |
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