Neurocognition as a major predictor of 8-week response to antipsychotics for drug-naïve first-episode schizophrenia using machine learning

Abstract Cognitive impairments are generally observed in patients with schizophrenia. However, it is unclear whether neurocognitive dysfunction can predict the efficacy of antipsychotics for first-episode schizophrenia (FES). Machine learning methods provide a relatively unbiased approach when evalu...

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Bibliographic Details
Main Authors: Xianghe Wang, Tianqi Gao, Xiaodong Guo, Bingjie Huang, Yunfei Ji, Wanheng Hu, Xiaolin Yin, Yue Zheng, Chengcheng Pu, Xin Yu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-025-00640-y
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