Aurantio-obtusin improves obesity and protects hepatic inflammation by rescuing mitochondrial damage in overwhelmed brown adipose tissue

Aurantio-obtusin improves obesity and protects hepatic inflammation by rescuing mitochondrial damage in overwhelmed brown adipose tissue

Abstract Background Obesity is frequently linked to chronic systamic inflammation and presents significant challenges to public health. Aurantio-obtusin (AO) boosted the brown adipose tissue (BAT) thermogenesis in diet-induced obesity. However, the specific mechanisms by which injured mitochondria-r...

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Bibliographic Details
Main Authors: Ruiyu Wu, Runping Liu, Ranyun Chen, Yijie Li, Xiaoyong Xue, Yinhao Zhang, Fanghong Li, Jiaorong Qu, Lingling Qin, Chen Wang, Xiaojiaoyang Li
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Chinese Medicine
Subjects:
Obesity
Aurantio-obtusin
Brown adipose tissue
Mitochondrial DNA
Inflammation
Online Access:https://doi.org/10.1186/s13020-025-01097-y
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