RORγt Mediates Angiotensin II‐Induced Pressor Responses, Microglia Activation, and Neuroinflammation by Disrupting the Blood–Brain Barrier in Rats
Background The RORγt (nuclear receptor retinoid‐related orphan receptor γt) has been identified as a master transcription factor critical for the differentiation of T helper 17 cells, the primary source of IL‐17A (interleukin‐17A). We previously demonstrated that IL‐17A promotes neuroinflammation an...
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| Main Authors: | Yang Yu, Baojian Xue, Lei Tong, Alexander G. Bassuk, Alan K. Johnson, Shun‐Guang Wei |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-03-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.124.040461 |
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