Reverse-engineering the FLT3-PI3K/AKT axis to enhance TILs function and improve prognosis in ovarian and cervical cancers

Abstract Background Ovarian cancers (OC) and cervical cancers (CC) have poor survival rates. Tumor-infiltrating lymphocytes (TILs) play a pivotal role in prognosis, but shared immune mechanisms remain elusive. Methods We integrated single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (...

Full description

Saved in:
Bibliographic Details
Main Authors: Feng Hao, Zhang Yan, Luo Shen, Wang Hui, Qiu Ling, Yang Xiaoyu, Jiang Hua
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-025-01592-8
Tags: Add Tag
No Tags, Be the first to tag this record!