Operating principles of interconnected feedback loops driving cell fate transitions

Abstract Interconnected feedback loops are prevalent across biological mechanisms, including cell fate transitions enabled by epigenetic mechanisms in carcinomas. However, the operating principles of these networks remain largely unexplored. Here, we identify numerous interconnected feedback loops i...

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Bibliographic Details
Main Authors: Mubasher Rashid, Abhiram Hegade
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-024-00483-w
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