Efficient solid-phase extraction of oligo-DNA from complex media using a nitrocellulose membrane modified with carbon nanotubes and aminated reduced graphene oxide

Efficient solid-phase extraction of oligo-DNA from complex media using a nitrocellulose membrane modified with carbon nanotubes and aminated reduced graphene oxide

Abstract Oligonucleotides are essential for gene regulation, expression, and disease biomarker identification, yet their small size presents challenges due to lower abundance and increased susceptibility to degradation in biological samples. Addressing these challenges, a novel approach was develope...

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Bibliographic Details
Main Authors: Georgian Alin Toader, Daniel Ioan Mihalache, Valentin Titus Grigorean, Elena Alina Chiticaru, Madalina Andreea Pandele, Mariana Ionita
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Quenching
Fluorescence
ssDNA
Nitrocellulose membrane
Graphene
Carbon nanotubes
Online Access:https://doi.org/10.1038/s41598-025-89705-7
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https://doi.org/10.1038/s41598-025-89705-7

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