Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis

Subglottic Eosinophilic Angiocentric Fibrosis (EAF) is an extremely rare disease of an elusive aetiology. It is chronically progressive benign condition that causes narrowing of the subglottic region leading to dysphonia and airway compromise. The diagnosis is historical and imaging is nonspecific....

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Main Authors: Ivan Keogh, Rohana O’Connell, Sean Hynes, John Lang
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2017/2381786
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author Ivan Keogh
Rohana O’Connell
Sean Hynes
John Lang
author_facet Ivan Keogh
Rohana O’Connell
Sean Hynes
John Lang
author_sort Ivan Keogh
collection DOAJ
description Subglottic Eosinophilic Angiocentric Fibrosis (EAF) is an extremely rare disease of an elusive aetiology. It is chronically progressive benign condition that causes narrowing of the subglottic region leading to dysphonia and airway compromise. The diagnosis is historical and imaging is nonspecific. We report a case xc of 56-year-old lady referred to our institution with globus sensation, hoarseness, and mild stridor. Incidental subglottic mass was found at time of diagnostic microlaryngoscopy and biopsy confirmed subglottic EAF. All laboratory investigations were unremarkable. Lesion was removed with laryngeal microdebrider and three courses of intravenous dexamethasone were administered. Patient’s postoperative period was uneventful and had remained disease free for 1 year. To date, no consensus has been reached on the optimal treatment of subglottic EAF. We recommend regular follow-up to detect early recurrence.
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spelling doaj-art-3af189a4dc614a74b23f422fdd397f1d2025-02-03T06:11:25ZengWileyCase Reports in Otolaryngology2090-67652090-67732017-01-01201710.1155/2017/23817862381786Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the SubglottisIvan Keogh0Rohana O’Connell1Sean Hynes2John Lang3Otorhinolaryngology Department, University College Hospital Galway and Academic Department of Otorhinolaryngology, National University of Ireland Galway, Newcastle Road, Galway, IrelandOtorhinolaryngology Department, University College Hospital Galway and Academic Department of Otorhinolaryngology, National University of Ireland Galway, Newcastle Road, Galway, IrelandDepartment of Pathology, University College Hospital Galway, Newcastle Road, Galway, IrelandOtorhinolaryngology Department, University College Hospital Galway and Academic Department of Otorhinolaryngology, National University of Ireland Galway, Newcastle Road, Galway, IrelandSubglottic Eosinophilic Angiocentric Fibrosis (EAF) is an extremely rare disease of an elusive aetiology. It is chronically progressive benign condition that causes narrowing of the subglottic region leading to dysphonia and airway compromise. The diagnosis is historical and imaging is nonspecific. We report a case xc of 56-year-old lady referred to our institution with globus sensation, hoarseness, and mild stridor. Incidental subglottic mass was found at time of diagnostic microlaryngoscopy and biopsy confirmed subglottic EAF. All laboratory investigations were unremarkable. Lesion was removed with laryngeal microdebrider and three courses of intravenous dexamethasone were administered. Patient’s postoperative period was uneventful and had remained disease free for 1 year. To date, no consensus has been reached on the optimal treatment of subglottic EAF. We recommend regular follow-up to detect early recurrence.http://dx.doi.org/10.1155/2017/2381786
spellingShingle Ivan Keogh
Rohana O’Connell
Sean Hynes
John Lang
Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
Case Reports in Otolaryngology
title Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_full Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_fullStr Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_full_unstemmed Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_short Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis
title_sort eosinophilic angiocentric fibrosis as a stenosing lesion in the subglottis
url http://dx.doi.org/10.1155/2017/2381786
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