Small extracellular vesicles derived from umbilical cord mesenchymal stem cells alleviate radiation-induced cardiac organoid injury

Small extracellular vesicles derived from umbilical cord mesenchymal stem cells alleviate radiation-induced cardiac organoid injury

Abstract Background Radiation-induced heart disease (RIHD) is one of the most serious complications of radiation therapy (RT) for thoracic tumors, and new interventions are needed for its prevention and treatment. Small extracellular vesicles (sEVs) from stem cells have attracted much attention due...

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Bibliographic Details
Main Authors: Hu Cao, Liang Yue, Jingyuan Shao, Fanxuan Kong, Shenghua Liu, Hongyu Huai, Zhichao He, Zhuang Mao, Yuefeng Yang, Yingxia Tan, Hua Wang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Stem Cell Research & Therapy
Subjects:
Radiation-induced heart disease
Mesenchymal stem cells
Small extracellular vesicles
Cardiac organoids
Mitochondrial function
Online Access:https://doi.org/10.1186/s13287-024-04115-2
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