HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

Several studies have previously shown that histone deacetylase 4 (HDAC4) can regulate endoplasmic reticulum stress‐induced apoptosis through the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway, thereby affecting the progression of osteoarthr...

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Bibliographic Details
Main Authors: Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:FEBS Open Bio
Subjects:
apoptosis
ATF4/CHOP signaling pathway
HDAC4
osteoarthritis
transgenic mouse
Online Access:https://doi.org/10.1002/2211-5463.13965
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https://doi.org/10.1002/2211-5463.13965

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